Adrafinil

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Adrafinil is a compound that is metabolized to modafinil and armodafinil in the body. Although modafinil is a controlled substance in most countries, adrafinil is largely unscheduled. In the United States, it is treated as a "supplement" despite having active metabolites that are recognized and regulated as drugs.

Legality and Availability[edit]

Modafinil[edit]

Modafinil
Legal Status
US Rx Only (Schedule IV)
Canada Rx Only (Schedule F)
UK Rx Only
AU Rx Only (Schedule 4)
Drug Information
FDA Status Drug
Class Stimulant
Addiction Risk Low
Brand Names Us-flag.png Eu-flag.png Provigil
In-flag.png Modalert
In-flag.png Modvigil

The United States is one of the only countries which considers modafinil a controlled substance. It is classified as Schedule IV under the CSA.

Canada and the United Kingdom classify modafinil as prescription-only, but uncontrolled. Australia classifies it as Schedule 4 (prescription only, uncontrolled).

Armodafinil[edit]

Armodafinil
Legal Status
US Rx Only (Schedule IV)
Drug Information
FDA Status Drug
Class Stimulant
Addiction Risk Low
Brand Names Us-flag.png Eu-flag.png Nuvigil
In-flag.png Waklert
In-flag.png Artvigil


The United States classifies armodafinil as a Schedule IV controlled substance.

Other countries typically regulate it as prescription-only but uncontrolled, similar to modafinil.

Adrafinil[edit]

Adrafinil
Legal Status
US Legal, unscheduled
Canada
AU Rx Only (Schedule 4)
Drug Information
FDA Status Unregulated
Class Stimulant
Addiction Risk Low


A prodrug to modafinil and armodafinil, adrafinil is largely unregulated. It is absent from the list of controlled substances in the United States.

Adrafinil was marketed in France under the brand name Olmifon until it was discontinued in 2011, as it was considered analogous to the already marketed modafinil.