Benzodiazepine Equivalency Chart

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This lists the relative potency of various benzo drugs.[1][2] Potencies are compared to that of diazepam, the classical benzodiazepine.

Relative Potency Typical Dose Drug Name Brand Names Onset of Action[3] Peak of Action[4] Half Life[5] Duration of Action[6] Legality
1/2 20 mg Oxazepam Serax 2-4 hr 1-4 hr 8 hr (3-25 hr) Controlled
1 10 mg Diazepam Valium 30 minutes 1-2 hr 100 hr 4-6 hr Controlled
10 1 mg Lorazepam Ativan 30-60 minutes 1-4 hr 15 hr (8-24 hr) 4-6 hr Controlled
10 1 mg Etizolam Au-flag.png De-flag.png Controlled
Us-flag.png Ca-flag.png Uk-flag.png Unscheduled
15Note 1 0.75Note 1 Alprazolam Xanax 30 minutes 1-2 hr 12 hr (9 - 24 hr) 3-4 hr Controlled
20 0.5 mg Clonazepam Klonopin 1 hr 1-4 hr 34 hr (18 - 50 hr) 6-8 hr Controlled

1 Alprazolam (Xanax) is listed differently on different equivalency charts. It is listed as having 10 times the strength of Valium by Medscape[7], and 20 times the strength of Valium by Benzo.org.uk[8]. As seemingly no consensus exists, we have chosen to take the average of these two estimates.

References[edit]

  1. http://www.benzo.org.uk/bzequiv.htm
  2. http://emedicine.medscape.com/article/2172250-overview
  3. http://www.thecarlatreport.com/sites/default/files/2011%20TCPR%20Benzo%20Table.pdf
  4. http://emedicine.medscape.com/article/2172250-overview
  5. http://www.globalrph.com/benzodiazepine_calc.htm
  6. http://www.thecarlatreport.com/sites/default/files/2011%20TCPR%20Benzo%20Table.pdf
  7. http://emedicine.medscape.com/article/2172250-overview
  8. http://www.benzo.org.uk/bzequiv.htm