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Mescaline-containing cacti
Legal Status
US Legal for ornamental purposes
Pure mescaline illegal
CA Pure mescaline illegal
Peyote explicity legal
EU Nl-flag.png Fr-flag.png De-flag.png Pure mescaline illegal, peyote legal
AU Pure mescaline illegal
Cacti legal (NSW, TAS, VIC)
Cacti illegal (NT, QLD, WA)
Drug Information
FDA Classification Unregulated
Class Psychedelic
Onset of Action
Duration of Action
Addiction Risk Addiction-green.png Low

A variety of naturally-growing cacti contain mescaline, a psychedelic drug with properties similar to LSD and psilocybin. Mescaline-containing cacti are unique legally in that they are often legal to possess for "ornamental" purposes.

Legality and Availability[edit]

United States[edit]

The legal status of mescaline in the US is ambiguous.[1] Mescaline-containing cacti are legal for ornamental purposes, like poppies, but consumption is illegal.


Similar to LSD and psilocybin mushrooms, mescaline activates the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. It also activates the 5-HT2C receptor; the relevance of this is not known.

This binding profile suggests that antipsychotics such as haloperidol and trazodone would be effective in "killing a trip."[2][3]